- GnRH Agonists - Gonadotropin Releasing Hormone
Agonists are considered the safest reversible contraceptives, but
dosages and duration of efficacy are not well established for all
species; side effects are generally similar to those associated with
gonadectomy, especially the potential for weight gain unless diet is
controlled; they have not been effective in male artiodactyls. They have
not been tested in male suidae.
• Suprelorin® (deslorelin) Implant (F)
• Lupron® Injection (F)
- MGA Implant (F)
- Depo-Provera® (F)
- Improvest® (M or F)
- Synthetic progestins may cause endometritis, pyometra and hydrometra
- Pregnant artiodactyls contracepted with progestins may be especially susceptible to suppression of uterine contractions; progestins should only be administered to animals CONFIRMED not pregnant.
- Depo-Provera may be a particular problem in pregnant females, since length of efficacy is so variable (approximate range: 2-24 months)
- GnRH agonists may not be effective in male bovids; effectiveness unknown for other artiodactyls
- MGA feed and MGA liquid not recommended for suids; dose required for efficacy associated with side-effects. The PZP Vaccine is not effective either, because it will not elicit an immune response in suids.
Research and Monitoring
THE USE OF ANY CONTRACEPTIVE IN NON-DOMESTIC ANIMALS IS CONSIDERED EXPERIMENTAL
(M=MALE-DIRECTED, F=FEMALE-DIRECTED METHOD)